Hussein, Mohammed Salah and Shaqaqiq, RIdha A. Bdulmohsen Al and Aldhuaina, Khaled Mubarak and Al-qattan, Azhar Abdullah and Qaysi, Salwah Mohammed and Almutairi, Abdulrahman Mubarak and Bensgayan, Turki Bjad and Essa, Nada Essa Al and Albaqami, Fahad Mohammed and ALDoohan, Fawaz Abduljabbar and Aljohani, Afnan Abdullah Obeed and Alobaywi, Yousef Naif (2021) Etiology, Assessment and Management of WDHA (Watery Diarrhea, Hypokalemia, and Achlorhydria) and VIPoma. Journal of Pharmaceutical Research International, 33 (56B). pp. 69-75. ISSN 2456-9119
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Abstract
The syndrome of watery diarrhoea, hypokalemia, and achlorhydria (WDHA syndrome) is an uncommon disorder marked by severe, watery diarrhoea caused by non–beta pancreatic islet cell oversecretion of vasoactive intestinal peptide (VIP). The onset of the disease is gradual, and diagnosis is often months or years later. Long-term dehydration, electrolyte and acid-base abnormalities, and chronic renal failure are all linked to morbidity. Pancreatic endocrine tumours are extremely rare, with less than 10 incidences per million people. VIPomas are uncommon tumours that affect between 0.05 and 2.0 percent of people. The most prevalent symptom is diarrhoea, which affects at least 89 percent of patients. VIPoma is treated with a combination of medicine and surgery The goal of first medical treatment is to reduce symptoms and restore fluids and electrolytes as quickly as possible
Item Type: | Article |
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Subjects: | South Asian Archive > Medical Science |
Depositing User: | Unnamed user with email support@southasianarchive.com |
Date Deposited: | 08 Mar 2023 11:50 |
Last Modified: | 27 Apr 2024 07:52 |
URI: | http://article.journalrepositoryarticle.com/id/eprint/94 |